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 Products
Mitleben presents the most advanced gas analyzers for your research, and gives you a support to be accessible to fruitful results.

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Biogas CO Analyzer, BAS-1000 measures carbon monoxide (CO), hydrogen (H2) and methane (CH4) of low (LDL: 0.1 ppm) to high concentration in 3.5 min.

Biogas Acetone Analyzer, BAS-2000, measures acetone, isoprene and ethanol in 7.5 min.
We can also present other gas analyzers, such as H2S, acrolein, trimethylamine and so on. When you have an intention to research in biological field, please show the specifications to us. We welcome your inquiry anytime！

Biogas Hydrogen Analyzer, BAS-200 measures hydrogen in oral and breath gas, separately with the simplest manner. Portable-type！

Biogas Ammonia Analyzer, BAS-300 measures NH3 in oral gas with the simplest manner. Useful for oral care medicine！

Flatus Gas Monitor, BAS-700 is unique to monitor gastrointestinal movement. The first in the world！

We, Mitleben's BRAS*) give you a support of new research field relating biogas measurement with our abundant know-how on determination of low concentration of various gas component. BAS Series supply the unique feature which offers the compact and reliable analyzer with BRAS*).
*) BRAS is the abbreviation of Biogas Research Advisory Attendant System.

Contact us : info@mitleben.com







Biogas Analyzer Systems

Biogas CO Analyzer, BAS-1000

BAS-1000 is designed specially to apply the strict research in bio-medical fields, and measures simultaneously three (3) components: CO, H2, and CH4 in 3.5 min.
Features
  1. Sample volume is only 1.0ml
  2. High sensitivity; 0.1ppm resolution
  3. Reliable and rapid result.
  4. Simple operation and no elaborated training
  5. Special versatile soft ware, PowerChromeTM
  6. Exclusive GC, and economical
Principle and structure
BAS-1000 is a compact gas chromatographic analyzer with semiconductor gas detector
(SGD), specially designed for bio-research environment. BAS Series, which provides a compact, reliable and easy-operation, means the smart analyzer; SmArt-GCTM.
Principle Gas Chromatography/
Semiconductor Gas Sensor
(GC-SGD)
Meas. Components CO/H2/CH4
Resolution 0.1ppm
Sample Vol. 1.0 ml
Meas. Time 3.5 min
Carrier gas Ultra pure air (Tank)
Carrier gas flow about 15 ml/min
Standard gas 3-gas/1- concentration
(ppm/air balance)
Data obtained
Results are displayed after each measurement (3.5min after sample injection) like below. For multi-test, data are automatically saved as formatted with PowerChromTM Software. For your necessity of precision, calibration is able to be conducted any time.


Application
CO measurement: CO-content in aqueous solution, blood, cell, and so on. Breath gas, and other biogas
H2, or CH4 measurement: Breath, and other biogas

Contact us for more information to apply your special specimen.
info@mitleben.com






Biogas Analyzer Systems

Biogas Acetone Analyzer, BAS-2000


BAS-2000 is designed specially to apply to the strict research in bio-medical fields, and measures simultaneously three (3) components: acetone, isoprene, and ethanol in 7.5 min.
Features
  1. Sample volume is only 2.5ml
  2. High sensitivity; 0.1ppm resolution
  3. Reliable and rapid result.
  4. Simple operation and no elaborated training
  5. Special versatile soft ware, PowerChromeTM
  6. Exclusive GC, and economical
Principle and structure
BAS-2000 is a compact gas chromatographic analyzer with semiconductor gas detector (SGD), specially designed for bio-research environment. BAS Series, which provides a compact, reliable and easy-operation, means the smart analyzer; SmArt-GCTM.
Principle Gas Chromatography/
Semiconductor Gas Sensor
(GC-SGD)
Components Acetone/Isoprene/Ethanol
Resolution 0.1ppm
Sample Vol. 2.5 ml
Meas. Time 7.5 min
Carrier gas Ultra pure air (Tank)
Carrier gas flow About 150 ml/min
Standard gas 3-gas/1- concentration
(ppm/air balance)
Data obtained
Results are displayed after each measurement (7.5min after sample injection) like below. For multi-test, data are automatically saved as formatted with PowerChromTM Software. For your necessity of precision, calibration is able to be conducted any time.


Clinical significance of acetone:
  1. A reliable indicator of metabolism of lipids.
    Breath acetone is an indicator of ketogenic substances
  2. Indicator of the abnormality of carbohydrate metabolism: lack of insulin secretion
  3. Indicator of lack of carbohydrates: the sign of starvation.
(*)Concerning the significance of isoprene, up to now the evaluation of it has not been clarified. There has long been a hope that breath isoprene analyses could be a noninvasive diagnostic tool to assess blood cholesterol levels or cholesterol synthesis rate. However, significant analytical problems in breath isoprene analysis had limited the usefulness of these measurements. Here, it is expected that BAS-2000 will open this finally, and lead to the goal by your own research.

Contact us for more information.
info@mitleben.com





Biogas Analyzer Systems

(*) What is BRAS?

BRAS* is the abbreviation of Biogas Research Advisory Attendant System. BRAS* supports your biogas research from the beginning.
Recently, "bio-gasology" which studies movements of gas, such as NO, CO, or H2S in bio/medical, or physiological fields has been developing more actively, and shown that gas has the important roles in various clinical and physiological phenomena.
However, it is very un-accessible for the beginner of gas analysis. Then, we offer SmArt-GCTM, that is BAS Series Analyzers, a compact, reliable and easy-to-operate analyzer, and a research advisory attendant; BRAS* to your research site.

In the most superior laboratories, various professionals frequently co-works with medical researchers. The profession has surely accelerated the research advancement, and results.







Biogas Analyzer Systems
SmArt-GCTM =GC-SGD, will develop the future of breath gas analysis.



Figures show GC-SGD Analyzer system (above) and the gas sensor structure (below).


And the gas sensitivity of SGD is shown in figure below. We can see SGD has ability to detect combustible (inflammable) gases, including CO, H2, CH4, H2S with very low concentration as 0.1ppm. Then, SGD is a better GC detector than FID, FPD, or TCD. Besides, SGD is micro size, and less electrical consumption.



After all, GC-SGD Analyzer becomes very compact in size, reliable in precision and easy-to-operate. We call this analyzer SmArt-GCTM as defined as a compact gas chromatographic analyzer with a semiconductor gas detector (GC/SGD) for breath and biological specimen, and applied for clinical practice
The four (4) conditions necessary to clinical test instrument are:
1. Compact,
2. easy to operate,
3. reliable
4. and economical.
When you are interesting in determination of H2S, acrolein, and other biological gases, ask us immediately.

Contact us for more information to apply your special items.
info@mitleben.com






Biogas Analyzer Systems

Biogas Hydrogen Analyzer, BAS-200


Hydrogen is the product of anaerobes in human body. Hydrogen in breath reflects the movement of gastrointestinal flora1), and oral hydrogen is expected as a indicator of activity of oral anaerobes.

Reaction of anaerobes in digestive tract:
Carbohydrates + Anaerobes = H2 + SCFA (short chain fatty acid) + α

BAS-200 offers the easiest accessible way to hydrogen measurement with compact, portable, rapid, reliable and very economical. Therefore, it will be very useful for non-invasive test in gastrointestinal activity, and indicator of oral hygiene.
Recently, very attractive reports on hydrogen in the body have been introduced to influence much to our health maintenance; that is hydrogen has the SOD like action to attack reactive oxygen species (ROS) 2)3).

Features:
BAS-200 measures hydrogen in oral and breath gas, separately in one instrument with a small volume of gas.
  1. Carries a high sensitive and selective hydrogen gas sensor
  2. Operation is quite simple, result comes rapid
  3. The results are automatically printed out.
  4. Running cost is very few.
Biogas H2 Analyzer, BAS-200
Subject H2 in breath, or oral gas
Range 1-200 ppm
Principle Sensitive semiconductor gas detector
Measuring time 60sec for breath, 200sec for oral test
Sensor probe In situ H2 sensor
Sample volume about 15 ml
Electric AC Adapter(AC100V, 50/60Hz), 5W
Dimension/ Weight 255/ 120/ 45 mm, about 1kg



Applications
  1. For the evaluations after taking dietary fiber = Clinical Nutrition
  2. Non-invasive monitor of digestive tract = Useful in mass screening


References:
  1. Levitt, MD, Production and excretion of hydrogen gas in man. New Eng. J. Med., 1969：281, 122-127
  2. Neal RJ; Dietary fibre and health: The role of hydrogen production, Medical Hypotheses, 27:85-87, 1988
  3. Shirahata, M. et al; Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage. BBRC, 234(1):269-74, 1997
Contact us for more information.
info@mitleben.com






Biogas Analyzer Systems

Biogas Ammonia Analyzer, BAS-300
    (Under development, coming soon)


BAS-300 measures NH3 in oral cavity with the simplest way, and is useful for oral care medicine.
Ammonia formation ability is a good indicator to evaluate oral hygiene. Ueda H, who is the representative of Mitleben R&D Inc., invented AAM1) (Amplified Ammonia Method) in 1995 and developed it with the ammonia analyzer system (AttainTM) to Japanese dental market2)3).
BAS-300 is a entirely new version of AttainTM ; much simpler, rapid, and economical ammonia analyzer without any expendables, according to the AAM principle basically. And BAS-300 is hoped to be employed by more dentists as an indicator of the preventive dentistry in practice.
Oral hygiene analyzer system, AttainTM was developed in 1997, and has been sold in Japan,
since1998.
Biogas NH3 Analyzer, BAS-300
Subject NH3 in oral gas
Range 1-200 ppm
Basic Principle Amplified Ammonia Method (PAT.)
= Ammonia generated with 1% of aq. urea solution in oral cavity
Detection Selective semiconductor gas sensor
Measuring time About 5min per test
Sensor probe In situ NH3 sensor (See figure)
Sample volume about 15 ml
Electric AC Adapter(AC100V, 50/60Hz), 5W
Dimension/ Weight 255/ 120/ 45 mm, about 1kg
Features
  1. Unique "Ammonia Amplified Method" (AAM, PAT.) to evaluate oral hygiene
  2. Compact, and portable
  3. Easy-to-operate, no elaborated training
  4. Reliable, selective semiconductor NH3 sensor
  5. Economical, no expendables to detect NH3
Application
  1. To monitor treatment periodontal disease, and oral hygiene
  2. As an indicator of training plaque control and other oral care medicine
  3. For halitosis treatment
References

1) Ueda H., Development of Ammonia Measurement for Indicator of Oral Care, Edited: Kobashi K.; Koki seikagaku (Biochemistry of Breath), 86-91, MedicalReview Co. Tokyo, 1998 (Japanese)

2) Ueda H., et al; Clinical significance of the oral ammonia analyzer Attain for halitosis treatment. In abstracts of the 5th International Conference on Breath Odor. Tel Aviv: International Society for Breath Odor Research: 2001. p.41

3) Amano A., et al; Monitoring ammonia to assess halitosis, Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;94:692-696

Contact us for more information
info@mitleben.com






Biogas Analyzer Systems

Flatus Gas Monitor, BAS-700
A unique analyzer to monitor gastrointestinal movement by a flatus.
First in the world！


An important check point of the patient in daily clinical control is to know the gastrointestinal movement. One of the essentials is the generation of flatus. Flatus Gas Monitor, BAS-700 is monitoring generation of flatus for 24hrs, and records every output time of flatus. This unique gas analyzer is the first in the world to apply gastrointestinal activity in practice, and is expected to use in clinical site widely.
Flatus Gas Monitor, BAS-700
Meas. subject Inflammable gas, such as hydrogen
Detector Sensitive semiconductor gas sensor
Threshold 100 counts increase per 15 sec
Sample Vol 200ml/min, continuous suction
Sample pump Calm air pump: diaphragm type
Report of detection Flashing of orange lamp
Record method Installed printer: flatus time, level, No. etc
(Output : RS232C 8bit 19200bps ASCII)
Dimension/Weight 240w/220D/80H mm, 2.5kg
Electrical AC100V, 5W

Features
BAS-700 is an useful labor-saving device for controlling gastrointestinal movement of postoperation, for example.
  1. Compact and easy-to-operate, no elaborated training
  2. Installed at side of bed, and monitored for 24hrs.
  3. Every flatus is recorded: the time, level and repeats.
  4. If necessary, output signal is saved in computer.
  5. Economical: expendables is just only a tube for sampling


Application
  1. First flatus monitoring of post-operation
  2. As an index of activity of bowel function
  3. For controlling of living body of old aged person
Reference

1) Yukioka H, Bogod DG, Rosen M; Recovery of bowel motility after surgery. Detection of time of first flatus from carbon dioxide concentration and patient estimate after nalbuphine and placebo. Br J Anaesth: 59: 581-584, 1987
2) Terai K, Yukioka H, Ueda H , Tanaka M: Detection of Flatus Using a Portable Hydrogen Analyzer, J Clin Anesth, 15, 570-571, 2003
3) Terai t., Ueda H. and Yukioka H., Flatus Monitor-flatus as index of bowel function-, J Jap. Assoc. Odor Environ. 36(5), 275-279, 2005 (Japanese)

Contact us for more information.
info@mitleben.com




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